Objective:
\nThulium fibre laser has emerged as an alternative to Holmium:YAG laser lithotripsy for ureteroscopic management of kidney stone disease. However, real-world comparative data from the United Kingdom remain limited. This study compared outcomes following thulium fibre laser and Holmium:YAG laser lithotripsy during ureteroscopy.<\/p>\n
Methods:
\nA retrospective matched analysis was performed of adult patients undergoing ureteroscopy with laser lithotripsy for kidney stone disease at a single tertiary centre between September 2023 and July 2025. The co-primary outcomes were endoscopic stone-free rate and radiological SFR at follow-up. Secondary outcomes included operative time, number of procedures, length of stay, stent indwelling time, and complications.<\/p>\n
Results:
\nFollowing matching, 47 patients were included in each group. Baseline characteristics were comparable, although bilateral stones and ureteral access sheath use were more common in the Holmium:YAG group. Endoscopic stone-free rate was similar between groups (93.6% Holmium:YAG vs 97.9% thulium fibre laser; p\u2009=\u20090.617). Radiological SFR was higher in the thulium fibre laser group for all patients (85.1% vs 91.5%; p\u2009=\u20090.06) and also for patients with single stones (80% vs 97.8%; p\u2009=\u20090.014). Holmium:YAG was associated with a higher mean number of procedures (1.6 vs 1.1; p\u2009<\u20090.001) and longer stent indwelling time (24.6 vs 19.0\u2009days; p\u2009=\u20090.010). Complication rates were low and did not differ significantly.<\/p>\n
Conclusion:
\nBoth thulium fibre laser and Holmium:YAG achieved comparable endoscopic stone-free rates following ureteroscopy. Thulium fibre laser was associated with higher stone clearance at radiological follow-up, required fewer procedures per patient and was associated with shorter stent dwell times. Further prospective multicentre studies are needed to confirm these findings and evaluate their cost-effectiveness.<\/p>","protected":false},"excerpt":{"rendered":"
Objective: Thulium fibre laser has emerged as an alternative to Holmium:YAG laser lithotripsy for ureteroscopic management of kidney stone disease. However, real-world comparative data from the United Kingdom remain limited. This study compared outcomes following thulium fibre laser and Holmium:YAG … read more<\/a><\/p>","protected":false},"author":3,"featured_media":333,"menu_order":0,"template":"","meta":{"_acf_changed":false},"portfolio-type":[19],"portfolio-tag":[],"class_list":["post-332","portfolio","type-portfolio","status-publish","has-post-thumbnail","hentry","portfolio-type-unmoderated-posters"],"acf":[],"_links":{"self":[{"href":"https:\/\/ice26.eposter.civired.com\/en\/wp-json\/wp\/v2\/portfolio\/332","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ice26.eposter.civired.com\/en\/wp-json\/wp\/v2\/portfolio"}],"about":[{"href":"https:\/\/ice26.eposter.civired.com\/en\/wp-json\/wp\/v2\/types\/portfolio"}],"author":[{"embeddable":true,"href":"https:\/\/ice26.eposter.civired.com\/en\/wp-json\/wp\/v2\/users\/3"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/ice26.eposter.civired.com\/en\/wp-json\/wp\/v2\/media\/333"}],"wp:attachment":[{"href":"https:\/\/ice26.eposter.civired.com\/en\/wp-json\/wp\/v2\/media?parent=332"}],"wp:term":[{"taxonomy":"portfolio-type","embeddable":true,"href":"https:\/\/ice26.eposter.civired.com\/en\/wp-json\/wp\/v2\/portfolio-type?post=332"},{"taxonomy":"portfolio-tag","embeddable":true,"href":"https:\/\/ice26.eposter.civired.com\/en\/wp-json\/wp\/v2\/portfolio-tag?post=332"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}